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1

Serine carboxypeptidases. A review

Journal:

Carlsberg Research Communications

Année:

1986

Langue:

english

Fichier:

PDF, 3.37 MB

english, 1986

2

Acceleration of yeast autolysis by chemical methods for production of intracellular enzymes

Klaus Breddam, Thorkild Beenfeldt

Journal:

Applied Microbiology and Biotechnology

Année:

1991

Langue:

english

Fichier:

PDF, 748 KB

english, 1991

3

C-Terminal Incorporation of Fluorogenic and Affinity Labels Using Wild-Type and Mutagenized Carboxypeptidase Y

Henning R. Stennicke, Kjeld Olesen, Steen Bech Sørensen, Klaus Breddam

Journal:

Analytical Biochemistry

Année:

1997

Langue:

english

Fichier:

PDF, 165 KB

english, 1997

4

Reversed-Flow Affinity Elution Applied to the Purification of Carboxypeptidase Y

Uffe H. Mortensen, Henning R. Stennicke, Klaus Breddam

Journal:

Analytical Biochemistry

Année:

1998

Langue:

english

Fichier:

PDF, 79 KB

english, 1998

5

Peptide Substrates Dissolved in Dimethylformamide May Be Modified at the ϵ-Amino Group of Lysyl Residues, Causing Erroneous Kinetic Characterization of Proteolytic Enzymes

Kjeld Olesen, Klaus Breddam

Journal:

Analytical Biochemistry

Année:

1998

Langue:

english

Fichier:

PDF, 54 KB

english, 1998

6

Binding of mercury (II) to protein thiol groups: A study of proteinase K and carboxypeptidase Y

Sven Bagger, Birgitte R. Byberg, Klaus Breddam

Journal:

Journal of Inorganic Biochemistry

Année:

1991

Langue:

english

Fichier:

PDF, 413 KB

english, 1991

7

A conserved glutamic acid bridge in serine carboxypeptidases, belonging to the α/β hydrolase fold, acts as a pH-dependent protein-stabilizing element

Uffe H. Mortensen, Klaus Breddam

Journal:

Protein Science

Année:

1994

Langue:

english

Fichier:

PDF, 479 KB

english, 1994

8

Characterization of the S1 binding site of the glutamic acid-specific protease from Streptomyces griseus

Henning R. Stennicke, Klaus Breddam, Jens J. Birktoft

Journal:

Protein Science

Année:

1996

Langue:

english

Fichier:

PDF, 3.85 MB

english, 1996

9

The specificity of carboxypeptidase Y may be altered by changing the hydrophobicity of the S'1 binding pocket

Steen Bech Sørensen, Klaus Breddam

Journal:

Protein Science

Année:

1997

Langue:

english

Fichier:

PDF, 590 KB

english, 1997

10

Semisynthesis of human insulin utilizing chemically modified carboxypeptidase Y

Klaus Breddam, Jack T. Johansen

Journal:

Carlsberg Research Communications

Année:

1984

Langue:

english

Fichier:

PDF, 688 KB

english, 1984

11

Primary structure of carboxypeptidase III from malted barley

Sørensen, Steen Bech, Svendsen, Ib, Breddam, Klaus

Journal:

Carlsberg Research Communications

Année:

1989

Langue:

english

Fichier:

PDF, 672 KB

english, 1989

12

Carboxypeptidase Y catalyzed transpeptidation and condensation reactions

Klaus Breddam, Jack T. Johansen, Martin Ottesen

Journal:

Carlsberg Research Communications

Année:

1984

Langue:

english

Fichier:

PDF, 389 KB

english, 1984

13

Malt carboxypeptidase catalyzed aminolysis reactions

Klaus Breddam, Martin Ottesen

Journal:

Carlsberg Research Communications

Année:

1984

Langue:

english

Fichier:

PDF, 611 KB

english, 1984

14

Carboxypeptidase S-1 from Penicillium janthinellum: Enzymatic properties in hydrolysis and aminolysis reactions

Journal:

Carlsberg Research Communications

Année:

1988

Langue:

english

Fichier:

PDF, 828 KB

english, 1988

15

Inactivation of carboxypeptidase Y by mutational removal of the putative essential histidyl residue

Bech, Lene M., Breddam, Klaus

Journal:

Carlsberg Research Communications

Année:

1989

Langue:

english

Fichier:

PDF, 541 KB

english, 1989

16

Modification of the single sulfhydryl group of carboxypeptidase Y with mercurials. Influence on enzyme specificity

Journal:

Carlsberg Research Communications

Année:

1983

Langue:

english

Fichier:

PDF, 731 KB

english, 1983

17

Influence of the substrate structure on carboxypeptidase Y catalyzed peptide bond formation

Klaus Breddam, Fred Widmer, Jack T. Johansen

Journal:

Carlsberg Research Communications

Année:

1980

Langue:

english

Fichier:

PDF, 481 KB

english, 1980

18

Carboxypeptidase Y catalyzed transpeptidations and enzymatic peptide synthesis

Klaus Breddam, Fred Widmer, Jack T. Johansen

Journal:

Carlsberg Research Communications

Année:

1980

Langue:

english

Fichier:

PDF, 761 KB

english, 1980

19

Influence of the structure of amine components on carboxypeptidase Y catalyzed amide bond formation

Fred Widmer, Klaus Breddam, Jack T. Johansen

Journal:

Carlsberg Research Communications

Année:

1981

Langue:

english

Fichier:

PDF, 684 KB

english, 1981

20

Primary structure of carboxypeptidase I from malted barley

Steen Bech Sørensen, Klaus Breddam, Ib Svendsen

Journal:

Carlsberg Research Communications

Année:

1986

Langue:

english

Fichier:

PDF, 693 KB

english, 1986

21

Increased hydrophobicity of the S′1binding site in carboxypeptidase Y obtained by site-directed mutagenesis

Jakob R. Winther, Morten C. Kielland-Brandt, Klaus Breddam

Journal:

Carlsberg Research Communications

Année:

1985

Langue:

english

Fichier:

PDF, 976 KB

english, 1985

22

Enzymatic properties of malt carboxypeptidase II in hydrolysis and aminolysis reactions

Journal:

Carlsberg Research Communications

Année:

1985

Langue:

english

Fichier:

PDF, 994 KB

english, 1985

23

Isolation of carboxypeptidase II from malted barley by affinity chromatography

Klaus Breddam, Steen Bech Sørensen, Martin Ottesen

Journal:

Carlsberg Research Communications

Année:

1985

Langue:

english

Fichier:

PDF, 873 KB

english, 1985

24

Isolation of carboxypeptidase III from malted barley by affinity chromatography

Klaus Breddam, Steen Bech Sørensen

Journal:

Carlsberg Research Communications

Année:

1987

Langue:

english

Fichier:

PDF, 630 KB

english, 1987

25

Primary structure of carboxypeptidase II from malted barley

Steen Bech Sørensen, Ib Svendsen, Klaus Breddam

Journal:

Carlsberg Research Communications

Année:

1987

Langue:

english

Fichier:

PDF, 693 KB

english, 1987

26

The free sulfhydryl group (Cys341) of carboxypeptidase Y: Functional effects of mutational substitutions

Jakob R. Winther, Klaus Breddam

Journal:

Carlsberg Research Communications

Année:

1987

Langue:

english

Fichier:

PDF, 786 KB

english, 1987

27

Primary structure and enzymatic properties of carboxypeptidase II from wheat bran

Klaus Breddam, Steen Bech Sørensen, Ib Svendsen

Journal:

Carlsberg Research Communications

Année:

1987

Langue:

english

Fichier:

PDF, 1021 KB

english, 1987

28

Mutational replacement of methionine by arginine in the S′1substrate binding site of yeast carboxypeptidase

Lene M. Bech, John Nielsen, Jakob R. Winther, Morten C. Kielland-Brandt, Klaus Breddam

Journal:

Carlsberg Research Communications

Année:

1986

Langue:

english

Fichier:

PDF, 524 KB

english, 1986

29

Modification of amino acid residues in the S1′binding site of carboxypeptidase Y

Journal:

Carlsberg Research Communications

Année:

1984

Langue:

english

Fichier:

PDF, 820 KB

english, 1984

30

Identification of methionyl and cysteinyl residues in the substrate binding site of carboxypeptidase Y

Klaus Breddam, IB Svendsen

Journal:

Carlsberg Research Communications

Année:

1984

Langue:

english

Fichier:

PDF, 474 KB

english, 1984

31

Chemically modified carboxypeptidase Y with increased amidase activity

Journal:

Carlsberg Research Communications

Année:

1984

Langue:

english

Fichier:

PDF, 1.37 MB

english, 1984

32

Influence of guanidine derivatives on the specificity of malt carboxypeptidase

Klaus Breddam, Martin Ottesen

Journal:

Carlsberg Research Communications

Année:

1983

Langue:

english

Fichier:

PDF, 665 KB

english, 1983

33

Amino acid methyl esters as amine components in CPD-Y catalyzed peptide synthesis: Control of side reactions

Klaus Breddam, Fred Widmer, Jack T. Johansen

Journal:

Carlsberg Research Communications

Année:

1983

Langue:

english

Fichier:

PDF, 422 KB

english, 1983

34

Isolation of a carboxypeptidase from malted barley by affinity chromatography

Klaus Breddam, Steen Bech Sørensen

Journal:

Carlsberg Research Communications

Année:

1983

Langue:

english

Fichier:

PDF, 1005 KB

english, 1983

35

Carboxypeptidase Y catalyzed C-terminal modification in the B-chain of porcine insulin

Klaus Breddam, Fred Widmer, Jack T. Johansen

Journal:

Carlsberg Research Communications

Année:

1981

Langue:

english

Fichier:

PDF, 847 KB

english, 1981

36

Determination of C-terminal sequences by digestion with serine carboxypeptidases: The influence of enzyme specificity

Klaus Breddam, Martin Ottesen

Journal:

Carlsberg Research Communications

Année:

1987

Langue:

english

Fichier:

PDF, 646 KB

english, 1987

37

Cyanylation of the single sulfhydryl group in carboxypeptidase Y with cyanogen bromide

Klaus Breddam, Anders Kanstrup

Journal:

Carlsberg Research Communications

Année:

1987

Langue:

english

Fichier:

PDF, 495 KB

english, 1987

38

A novel carboxylesterase from Aspergillus niger and its hydrolysis of succinimide esters

Li Xiaoming, Klaus Breddam

Journal:

Carlsberg Research Communications

Année:

1989

Langue:

english

Fichier:

PDF, 594 KB

english, 1989

39

Carboxypeptidase Y catalyzed C-terminal modifications of peptides

Klaus Breddam, Fred Widmer, Jack T. Johansen

Journal:

Carlsberg Research Communications

Année:

1981

Langue:

english

Fichier:

PDF, 598 KB

english, 1981

40

Carboxypeptidase Y catalyzed peptide synthesis using amino acid alkyl esters as amine components

Fred Widmer, Klaus Breddam, Jack T. Johansen

Journal:

Carlsberg Research Communications

Année:

1980

Langue:

english

Fichier:

PDF, 700 KB

english, 1980

41

Chemical modifications of a cysteinyl residue introduced in the binding site of carboxypeptidase Y by site-directed mutagenesis

Lene M. Bech, Klaus Breddam

Journal:

Carlsberg Research Communications

Année:

1988

Langue:

english

Fichier:

PDF, 848 KB

english, 1988

42

Anthranilamide and nitrotyrosine as a donor-acceptor pair in internally quenched fluorescent substrates for endopeptidases: Multicolumn peptide synthesis of enzyme substrates for subtilisin carlsberg and pepsin

Morten Meldal, Klaus Breddam

Journal:

Analytical Biochemistry

Année:

1991

Langue:

english

Fichier:

PDF, 800 KB

english, 1991

43

Silyl protection in the solid-phase synthesis of N-linked glycopeptides. Preparation of glycosylated fluorogenic substrates for subtilisins

Ida Christiansen-Brams, Anita M. Jansson, Morten Meldal, Klaus Breddam, Klaus Bock

Journal:

Bioorganic & Medicinal Chemistry

Année:

1994

Langue:

english

Fichier:

PDF, 3.66 MB

english, 1994

44

Amidation of growth hormone releasing factor (1–29) by serine carboxypeptidase catalysed transpeptidation

KLAUS BREDDAM, FRED WIDMER, MORTEN MELDAL

Journal:

Chemical Biology & Drug Design

Année:

1991

Langue:

english

Fichier:

PDF, 708 KB

english, 1991

45

Peptide synthesis catalyzed by the Glu/Asp-specific endopeptidase : Influence of the ester leaving group of the acyl donor on yield and catalytic eficiency

JACOB BONGERS, WEN LIU, THEODORE LAMBROS, KLAUS BREDDAM, ROBERT M. CAMPBELL, ARTHUR M. FELIX, EDGAR P. HEIMER

Journal:

Chemical Biology & Drug Design

Année:

1994

Langue:

english

Fichier:

PDF, 613 KB

english, 1994

46

A highly active and oxidation-resistant subtilisin-like enzyme produced by a combination of site-directed mutagenesis and chemical modification

Hanne GRØN, Lene M. BECH, Sven BRANNER, Klaus BREDDAM

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 573 KB

english, 1990

47

Isolation and amino acid sequence of a glutamic acid specific endopeptidase from Bacillus licheniformis

Ib SVENDSEN, Klaus BREDDAM

Journal:

Année:

1992

Langue:

english

Fichier:

PDF, 653 KB

english, 1992

48

Substrate preferences of glutamic-acid-specific endopeptidases assessed by synthetic Peptide Substrates based on intramolecular fluorescence quenching

Klaus BREDDAM, Morten MELDAL

Journal:

Année:

1992

Langue:

english

Fichier:

PDF, 475 KB

english, 1992

49

Mutational replacements in subtilisin 309 : Val104 has a modulating effect on the P4 substrate preference

Lene M. BECH, Steen Bech SØRENSEN, Klaus BREDDAM

Journal:

Année:

1992

Langue:

english

Fichier:

PDF, 650 KB

english, 1992

50

Peptide Aldehyde Complexes with Wheat Serine Carboxypeptidase II: Implications for the Catalytic Mechanism and Substrate Specificity

Timothy L. Bullock, Klaus Breddam, James S. Remington

Journal:

Journal of Molecular Biology

Année:

1996

Langue:

english

Fichier:

PDF, 1.09 MB

english, 1996